4HDA
Crystal structure of human Sirt5 in complex with Fluor-de-Lys peptide and resveratrol
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | NAD-dependent protein deacylase sirtuin-5, mitochondrial | polymer | 275 | 29913.1 | 2 | UniProt (Q9NXA8) Pfam (PF02146) In PDB | Homo sapiens (human) | Regulatory protein SIR2 homolog 5, SIR2-like protein 5 |
2 | F | Fluor-de-Lys peptide | polymer | 4 | 769.9 | 1 | |||
3 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
4 | B | RESVERATROL | non-polymer | 228.2 | 1 | Chemie (STL) | |||
5 | water | water | 18.0 | 15 | Chemie (HOH) |
Sequence modifications
A, B: 34 - 302 (UniProt: Q9NXA8)
PDB | External Database | Details |
---|---|---|
Gly 28 | - | expression tag |
Ile 29 | - | expression tag |
Asp 30 | - | expression tag |
Pro 31 | - | expression tag |
Phe 32 | - | expression tag |
Thr 33 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 60596.1 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 359.1 | |
All* | Total formula weight | 60955.1 |