4HBN
Crystal structure of the human HCN4 channel C-terminus carrying the S672R mutation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | polymer | 205 | 24211.7 | 1 | UniProt (Q9Y3Q4) Pfam (PF00027) | Homo sapiens (human) | |
| 2 | B (A) | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE | non-polymer | 329.2 | 1 | Chemie (CMP) PubChem (176488666) PubChem (6076) PubChem (23902375) PubChem (25322948) PubChem (40467852) PubChem (44629928) PubChem (25322946) PubChem (56973690) PubChem (216878) PubChem (59909322) PubChem (59968988) PubChem (70878457) PubChem (59350541) PubChem (3080770) PubChem (3246347) PubChem (274) PubChem (6604194) PubChem (6603718) PubChem (6713792) PubChem (6714006) PubChem (124132380) PubChem (12071879) PubChem (12866365) PubChem (163043517) PubChem (129317551) PubChem (131841987) PubChem (134693155) PubChem (138107790) PubChem (163043518) | |||
| 3 | C (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) PubChem (1061) | |||
| 4 | D (A) | water | water | 18.0 | 60 | Chemie (HOH) |
Sequence modifications
A: 521 - 724 (UniProt: Q9Y3Q4)
| PDB | External Database | Details |
|---|---|---|
| Ser 520 | - | expression tag |
| Arg 672 | Ser 672 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24211.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 424.2 | |
| All* | Total formula weight | 24635.9 |
