4HBN
Crystal structure of the human HCN4 channel C-terminus carrying the S672R mutation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | polymer | 205 | 24211.7 | 1 | UniProt (Q9Y3Q4) Pfam (PF00027) | Homo sapiens (human) | |
| 2 | B (A) | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE | non-polymer | 329.2 | 1 | Chemie (CMP) | |||
| 3 | C (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 4 | D (A) | water | water | 18.0 | 60 | Chemie (HOH) |
Sequence modifications
A: 521 - 724 (UniProt: Q9Y3Q4)
| PDB | External Database | Details |
|---|---|---|
| Ser 520 | - | expression tag |
| Arg 672 | Ser 672 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24211.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 424.2 | |
| All* | Total formula weight | 24635.9 |
