4HBM
Ordering of the N Terminus of Human MDM2 by Small Molecule Inhibitors
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | E3 ubiquitin-protein ligase Mdm2 | polymer | 120 | 13595.5 | 8 | UniProt (Q00987) Pfam (PF02201) In PDB | Homo sapiens (human) | Double minute 2 protein, Hdm2, Oncoprotein Mdm2, p53-binding protein Mdm2 |
2 | A, B, C, D, E... | {(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-[(2S)-1-hydroxybutan-2-yl]-2-oxopiperidin-3-yl}acetic acid | non-polymer | 450.4 | 8 | Chemie (0Y7) | |||
3 | water | water | 18.0 | 866 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 108764.2 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 3602.8 | |
All* | Total formula weight | 112367.1 |