4HBM

Ordering of the N Terminus of Human MDM2 by Small Molecule Inhibitors

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	E3 ubiquitin-protein ligase Mdm2	polymer	120	13595.5	8	UniProt (Q00987) Pfam (PF02201)	Homo sapiens (human)	Double minute 2 protein, Hdm2, Oncoprotein Mdm2, p53-binding protein Mdm2
2	I, J, K, L, M... (A, B, C, D, E...)	{(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-[(2S)-1-hydroxybutan-2-yl]-2-oxopiperidin-3-yl}acetic acid	non-polymer		450.4	8	Chemie (0Y7)
3	Q, R, S, T, U... (A, B, C, D, E...)	water	water		18.0	866	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	108764.2
Non-Polymers*	Number of molecules	8
	Total formula weight	3602.8
All*	Total formula weight	112367.1

*Water molecules are not included.