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4HAB

Crystal structure of Plk1 Polo-box domain in complex with PL-49

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Serine/threonine-protein kinase PLK1polymer22325813.53UniProt (P53350)
Pfam (PF00659)
Homo sapiens (human)Polo-like kinase 1, PLK-1, Serine/threonine-protein kinase 13, STPK13
2D, E, F
(D, E, F)
PL-49polymer7860.03BIRD (PRD_000780)synthetic construct
3G, H, J, K, L
(A, B, C)
3-CYCLOHEXYL-1-PROPYLSULFONIC ACIDnon-polymer221.35Chemie (CXS)
4I
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
5M, N, O, P, Q...
(A, B, C, D, E...)
waterwater18.056Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight80020.3
Non-Polymers*Number of molecules6
Total formula weight1201.6
All*Total formula weight81221.9
*Water molecules are not included.

237735

PDB entries from 2025-06-18

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