4HAB
Crystal structure of Plk1 Polo-box domain in complex with PL-49
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CXS A 601 |
| Chain | Residue |
| A | PHE436 |
| A | ASN437 |
| A | TRP514 |
| A | PHE515 |
| A | ARG516 |
| A | CXS602 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CXS A 602 |
| Chain | Residue |
| B | GLU504 |
| B | LEU505 |
| B | ALA506 |
| A | PHE515 |
| A | ARG516 |
| A | CXS601 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 A 603 |
| Chain | Residue |
| A | ASN385 |
| A | ARG584 |
| A | HOH704 |
| A | HOH725 |
| A | HOH726 |
| C | HIS538 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CXS B 601 |
| Chain | Residue |
| B | ASN437 |
| B | THR513 |
| B | TRP514 |
| B | PHE515 |
| B | ARG516 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CXS C 601 |
| Chain | Residue |
| B | LEU394 |
| B | VAL395 |
| C | PHE534 |
| C | SER578 |
| C | ARG581 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CXS C 602 |
| Chain | Residue |
| C | THR513 |
| C | TRP514 |
| C | ARG516 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18691976 |
| Chain | Residue | Details |
| A | SER375 | |
| A | SER450 | |
| B | SER375 | |
| B | SER450 | |
| C | SER375 | |
| C | SER450 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18691976 |
| Chain | Residue | Details |
| A | THR498 | |
| B | THR498 | |
| C | THR498 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:23455478 |
| Chain | Residue | Details |
| A | LYS492 | |
| B | LYS492 | |
| C | LYS492 |
