4H8J

Structure of GluA2-LBD in complex with MES

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Glutamate receptor 2	polymer	276	30400.9	4	UniProt (P19491) Pfam (PF10613) Pfam (PF00060) In PDB	Rattus norvegicus (rat)	GluR-2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2
2	A, C	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	2	Chemie (MES)
3	A, B, C, D	SULFATE ION	non-polymer		96.1	12	Chemie (SO4)
4	A, B, C, D	1,2-ETHANEDIOL	non-polymer		62.1	5	Chemie (EDO)
5		water	water		18.0	1089	Chemie (HOH)

Sequence modifications

A, B, C, D: 3 - 117 (UniProt: P19491)

PDB	External Database	Details
Gly -11	-	expression tag
Ser -10	-	expression tag
Ala -9	-	expression tag
Met -8	-	expression tag
Gly -7	-	expression tag
Ser -6	-	expression tag
Gly -5	-	expression tag
Asn -4	-	expression tag
Asp -3	-	expression tag
Thr -2	-	expression tag
Ser -1	-	expression tag
Arg 0	-	expression tag
Gly 1	-	expression tag
Ala 2	-	expression tag

A, B, C, D: 120 - 264 (UniProt: P19491)

PDB	External Database	Details
Gly 118	-	linker
Thr 119	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	121603.6
Non-Polymers*	Number of molecules	19
	Total formula weight	1853.6
All*	Total formula weight	123457.1

*Water molecules are not included.