4H54
Crystal structure of the diguanylate cyclase DgcZ
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Diguanylate cyclase YdeH | polymer | 304 | 34884.4 | 2 | UniProt (P31129) Pfam (PF13682) Pfam (PF00990) | Escherichia coli | DgcZ, DGC |
| 2 | C, H (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, F, I, K (A, B) | GUANOSINE-5'-RP-ALPHA-THIO-TRIPHOSPHATE | non-polymer | 539.2 | 4 | Chemie (GAV) | |||
| 4 | E, J (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | G (A) | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one) | non-polymer | 690.4 | 1 | Chemie (C2E) |
Sequence modifications
A, B: 2 - 296 (UniProt: P31129)
| PDB | External Database | Details |
|---|---|---|
| Ala 1 | - | expression tag |
| Ala 52 | Cys 52 | engineered mutation |
| Leu 297 | - | expression tag |
| Glu 298 | - | expression tag |
| His 299 | - | expression tag |
| His 300 | - | expression tag |
| His 301 | - | expression tag |
| His 302 | - | expression tag |
| His 303 | - | expression tag |
| His 304 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69768.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 3026.8 | |
| All* | Total formula weight | 72795.7 |
