4GYY
Crystal structure of human O-GlcNAc Transferase with UDP-5SGlcNAc and a peptide substrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | polymer | 723 | 80974.5 | 2 | UniProt (O15294) Pfam (PF13424) Pfam (PF13414) Pfam (PF13844) | Homo sapiens (human) | O-GlcNAc transferase subunit p110, O-linked N-acetylglucosamine transferase 110 kDa subunit, OGT |
| 2 | B, D (B, D) | Casein kinase II subunit alpha | polymer | 14 | 1398.6 | 2 | UniProt (P68400) | Homo sapiens | CK II alpha |
| 3 | E, H (A, C) | (2S,3R,4R,5S,6R)-3-(acetylamino)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-thiopyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate | non-polymer | 623.4 | 2 | Chemie (12V) | |||
| 4 | F, G, I (A, B, D) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 836 | Chemie (HOH) |
Sequence modifications
A, C: 313 - 1031 (UniProt: O15294)
B, D: 14 - 26 (UniProt: P68400)
| PDB | External Database | Details |
|---|---|---|
| Gly 309 | - | expression tag |
| Pro 310 | - | expression tag |
| Gly 311 | - | expression tag |
| Ser 312 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Tyr 13 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 164746.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1535.0 | |
| All* | Total formula weight | 166281.2 |
