4GYF
Crystal structure of histidinol phosphate phosphatase (HISK) from Lactococcus lactis subsp. lactis Il1403 complexed with ZN, L-histidinol and phosphate
Replaces: 3UMUEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histidinol-phosphatase | polymer | 284 | 33235.8 | 1 | UniProt (Q02150) Pfam (PF02811) | Lactococcus lactis subsp. lactis | HolPase |
| 2 | B, C, D, E (A) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | F (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 4 | G, H, I, J, K... (A) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
| 5 | M (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 6 | N, O (A) | L-histidinol | non-polymer | 142.2 | 2 | Chemie (HSO) | |||
| 7 | P, Q, R (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 8 | S (A) | water | water | 18.0 | 229 | Chemie (HOH) |
Sequence modifications
A: 4 - 271 (UniProt: Q02150)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | expression tag |
| Ser 2 | - | expression tag |
| Leu 3 | - | expression tag |
| Gln 65 | Arg 63 | engineered mutation |
| Thr 127 | Ile 125 | engineered mutation |
| Arg 217 | Lys 215 | engineered mutation |
| Lys 272 | - | expression tag |
| Leu 273 | - | expression tag |
| Ala 274 | - | expression tag |
| Ala 275 | - | expression tag |
| Ala 276 | - | expression tag |
| Leu 277 | - | expression tag |
| Glu 278 | - | expression tag |
| His 279 | - | expression tag |
| His 280 | - | expression tag |
| His 281 | - | expression tag |
| His 282 | - | expression tag |
| His 283 | - | expression tag |
| His 284 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33235.8 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1195.0 | |
| All* | Total formula weight | 34430.8 |
