4GMJ
Structure of human NOT1 MIF4G domain co-crystallized with CAF1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | CCR4-NOT transcription complex subunit 1 | polymer | 229 | 26629.0 | 3 | UniProt (A5YKK6) Pfam (PF16415) | Homo sapiens (human) | CCR4-associated factor 1, Negative regulator of transcription subunit 1 homolog, NOT1H, hNOT1 |
| 2 | B, D, F (B, D, F) | CCR4-NOT transcription complex subunit 7 | polymer | 285 | 32776.0 | 3 | UniProt (Q9UIV1) Pfam (PF04857) | Homo sapiens (human) | BTG1-binding factor 1, CCR4-associated factor 1, CAF-1 |
| 3 | G, H, K, L, M... (B, D, F) | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
| 4 | I, N, R (B, D, F) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | J, O, S (B, D, F) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 6 | U, V, W, X, Y... (A, B, C, D, E...) | water | water | 18.0 | 211 | Chemie (HOH) |
Sequence modifications
A, C, E: 1093 - 1317 (UniProt: A5YKK6)
| PDB | External Database | Details |
|---|---|---|
| His 1089 | - | expression tag |
| Met 1090 | - | expression tag |
| Leu 1091 | - | expression tag |
| Glu 1092 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 178215.0 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 577.1 | |
| All* | Total formula weight | 178792.1 |
