4GIW

Crystal structure of the RUN domain of human NESCA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	RUN and SH3 domain-containing protein 1	polymer	198	21829.9	2	UniProt (Q9BVN2) Pfam (PF02759)	Homo sapiens (human)	Nesca, New molecule containing SH3 at the carboxy-terminus
2	C, D (A, B)	water	water		18.0	149	Chemie (HOH)

Sequence modifications

A, B: 1 - 190 (UniProt: Q9BVN2)

PDB	External Database	Details
Mse 150	Leu 626	engineered mutation
Mse 152	Leu 628	engineered mutation
Leu 191	-	expression tag
Glu 192	-	expression tag
His 193	-	expression tag
His 194	-	expression tag
His 195	-	expression tag
His 196	-	expression tag
His 197	-	expression tag
His 198	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	43659.8
All*	Total formula weight	43659.8

*Water molecules are not included.