4GFX
Crystal structure of the N-terminal domain of TXNIP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Thioredoxin-interacting protein | polymer | 151 | 17057.5 | 1 | UniProt (Q9H3M7) Pfam (PF00339) | Homo sapiens (human) | TXNIP, Thioredoxin-binding protein 2, TBP-2, Vitamin D3 up-regulated protein 1, VDUP1 |
| 2 | B (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | C (A) | water | water | 18.0 | 100 | Chemie (HOH) |
Sequence modifications
A: 4 - 154 (UniProt: Q9H3M7)
| PDB | External Database | Details |
|---|---|---|
| Val 4 | Phe 4 | engineered mutation |
| Ala 5 | Lys 5 | engineered mutation |
| Ala 6 | Lys 6 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17057.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 17149.6 |
