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4GDL

Crystal Structure of Human Atg12~Atg5 Conjugate in Complex with an N-terminal Fragment of Atg16L1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Ubiquitin-like protein ATG12polymer9110282.01UniProt (O94817)
Pfam (PF04110)
Homo sapiens (human)Autophagy-related protein 12, APG12-like
2B
(B)
Autophagy protein 5polymer27532489.21UniProt (Q9H1Y0)
Pfam (PF20638)
Pfam (PF20637)
Pfam (PF04106)
Homo sapiens (human)APG5-like, Apoptosis-specific protein
3C
(C)
Autophagy-related protein 16-1polymer364657.41UniProt (Q676U5)Homo sapiens (human)APG16-like 1
4D
(B)
SODIUM IONnon-polymer23.01Chemie (NA)
Sequence modifications
A: 52 - 140 (UniProt: O94817)
PDBExternal DatabaseDetails
Gly 50-expression tag
Ser 51-expression tag
C: 11 - 43 (UniProt: Q676U5)
PDBExternal DatabaseDetails
Ser 8-expression tag
His 9-expression tag
Met 10-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight47428.7
Non-Polymers*Number of molecules1
Total formula weight23.0
All*Total formula weight47451.6
*Water molecules are not included.

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PDB entries from 2025-07-02

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