4GAH
Human acyl-CoA thioesterases 4 in complex with undecan-2-one-CoA inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Thioesterase superfamily member 4 | polymer | 209 | 23962.8 | 2 | UniProt (Q5T1C6) Pfam (PF03061) | Homo sapiens (human) | Carboxyl-terminal modulator protein |
| 2 | C, D, E (A, B) | [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3R)-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-4-[[3-oxidanylidene-3-[2-[(2R)-2-oxidanylundecyl]sulfanylethylamino]propyl]amino]butyl] hydrogen phosphate | non-polymer | 937.8 | 3 | Chemie (0ET) | |||
| 3 | F, G (A, B) | water | water | 18.0 | 211 | Chemie (HOH) |
Sequence modifications
A, B: 40 - 240 (UniProt: Q5T1C6)
| PDB | External Database | Details |
|---|---|---|
| Leu 241 | - | expression tag |
| Glu 242 | - | expression tag |
| His 243 | - | expression tag |
| His 244 | - | expression tag |
| His 245 | - | expression tag |
| His 246 | - | expression tag |
| His 247 | - | expression tag |
| His 248 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47925.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 2813.5 | |
| All* | Total formula weight | 50739.0 |
