4GA3
Crystal Structure of Human Farnesyl Diphosphate Synthase in Complex with BPH-1260
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Farnesyl pyrophosphate synthase | polymer | 348 | 40029.7 | 1 | UniProt (P14324) Pfam (PF00348) | Homo sapiens (human) | FPP synthase, FPS, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Geranyltranstransferase |
| 2 | B (A) | 1-butyl-3-(2-hydroxy-2,2-diphosphonoethyl)-1H-imidazol-3-ium | non-polymer | 329.2 | 1 | Chemie (4GA) | |||
| 3 | C, D, E (A) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 4 | F, G (A) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 5 | H (A) | water | water | 18.0 | 70 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40029.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 592.1 | |
| All* | Total formula weight | 40621.8 |
