4FZ3
Crystal structure of SIRT3 in complex with acetyl p53 peptide coupled with 4-amino-7-methylcoumarin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | polymer | 283 | 31397.1 | 1 | UniProt (Q9NTG7) Pfam (PF02146) In PDB | Homo sapiens (human) | hSIRT3, Regulatory protein SIR2 homolog 3, SIR2-like protein 3 |
| 2 | B | peptide from Cellular tumor antigen p53 | polymer | 6 | 796.0 | 1 | UniProt (P04637) In PDB | Homo sapiens | |
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | water | water | 18.0 | 163 | Chemie (HOH) |
Sequence modifications
A: 118 - 399 (UniProt: Q9NTG7)
B: 801 - 804 (UniProt: P04637)
| PDB | External Database | Details |
|---|---|---|
| Gly 117 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ace 800 | - | acetylation |
| Mcm 805 | - | amidation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32193.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 32258.5 |
