4FZ3
Crystal structure of SIRT3 in complex with acetyl p53 peptide coupled with 4-amino-7-methylcoumarin
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 401 |
| Chain | Residue |
| A | CYS256 |
| A | CYS259 |
| A | CYS280 |
| A | CYS283 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:29474172, ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| B | LYS803 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-methyllysine; by KMT5A; alternate => ECO:0000269|PubMed:17707234, ECO:0000269|PubMed:20870725, ECO:0000269|PubMed:22864287 |
| Chain | Residue | Details |
| B | ALY804 | |
| A | GLN228 | |
| A | GLY319 | |
| A | ASN344 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:19535340, ECO:0000269|PubMed:23897466 |
| Chain | Residue | Details |
| A | CYS256 | |
| A | CYS259 | |
| A | CYS280 | |
| A | CYS283 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:Q8R104 |
| Chain | Residue | Details |
| A | LYS122 |
