4FM9
Human topoisomerase II alpha bound to DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA topoisomerase 2-alpha | polymer | 763 | 88157.6 | 1 | UniProt (P11388) Pfam (PF01751) Pfam (PF16898) Pfam (PF00521) | Homo sapiens (human) | DNA topoisomerase II, alpha isozyme |
| 2 | B (C) | DNA (5'-D(P*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3') | polymer | 13 | 4080.7 | 1 | synthetic construct | ||
| 3 | C (D) | DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3') | polymer | 17 | 5099.3 | 1 | synthetic construct | ||
| 4 | D, F (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | G, H, I (A, C, D) | water | water | 18.0 | 44 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 97337.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 140.7 | |
| All* | Total formula weight | 97478.3 |
