4FK5
Structure of the SAGA Ubp8(S144N)/Sgf11/Sus1/Sgf73 DUB module
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ubiquitin carboxyl-terminal hydrolase 8 | polymer | 476 | 54060.7 | 1 | UniProt (P50102) Pfam (PF02148) Pfam (PF00443) | Saccharomyces cerevisiae (Baker's yeast) | Deubiquitinating enzyme 8, Ubiquitin thioesterase 8, Ubiquitin-specific-processing protease 8 |
| 2 | B (B) | Protein SUS1 | polymer | 96 | 11094.5 | 1 | UniProt (Q6WNK7) Pfam (PF10163) | Saccharomyces cerevisiae (Baker's yeast) | |
| 3 | C (C) | SAGA-associated factor 11 | polymer | 99 | 11297.6 | 1 | UniProt (Q03067) Pfam (PF18519) Pfam (PF08209) | Saccharomyces cerevisiae (Baker's yeast) | 11 kDa SAGA-associated factor |
| 4 | D (E) | SAGA-associated factor 73 | polymer | 96 | 10824.3 | 1 | UniProt (P53165) Pfam (PF18508) | Saccharomyces cerevisiae (Baker's yeast) | 73 kDa SAGA-associated factor, SAGA histone acetyltransferase complex 73 kDa subunit |
| 5 | E, F, G, H, I... (A, C, E) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 6 | K, N (A, C) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | L (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 8 | P, Q, R, S (A, B, C, E) | water | water | 18.0 | 396 | Chemie (HOH) |
Sequence modifications
A: 1 - 471 (UniProt: P50102)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Asn 144 | Ser 144 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 87277.1 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 769.5 | |
| All* | Total formula weight | 88046.6 |
