4FAT
Ligand-binding domain of GluA2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Glutamate receptor 2 | polymer | 263 | 29177.7 | 1 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) Pfam (PF00497) In PDB | Rattus norvegicus (brown rat rat rats) | GluR-2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2 |
| 2 | A | GLUTAMIC ACID | non-polymer | 147.1 | 1 | Chemie (GLU) | |||
| 3 | A | 2-({[4-(hydroxymethyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl}amino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide | non-polymer | 402.4 | 1 | Chemie (496) | |||
| 4 | A | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | A | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 6 | A | LITHIUM ION | non-polymer | 6.9 | 1 | Chemie (LI) | |||
| 7 | water | water | 18.0 | 389 | Chemie (HOH) |
Sequence modifications
A: 3 - 117 (UniProt: P19491)
A: 120 - 263 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Ala 2 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 118 | - | SEE REMARK 999 |
| Thr 119 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29177.7 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1213.0 | |
| All* | Total formula weight | 30390.7 |
