4FAO
Specificity and Structure of a high affinity Activin-like 1 (ALK1) signaling complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, G, H, M... | Growth/differentiation factor 2 | polymer | 110 | 12103.0 | 12 | UniProt (Q9UK05) Pfam (PF00019) In PDB | Homo sapiens (human) | GDF-2, Bone morphogenetic protein 9, BMP-9 |
2 | C, D, I, J, O... | Serine/threonine-protein kinase receptor R3 | polymer | 106 | 11592.9 | 12 | UniProt (P37023) In PDB | Homo sapiens (human) | SKR3, Activin receptor-like kinase 1, ALK-1, TGF-B superfamily receptor type I, TSR-I |
3 | E, F, K, L, Q... | Activin receptor type-2B | polymer | 124 | 14118.3 | 12 | UniProt (Q13705) Pfam (PF01064) In PDB | Homo sapiens (human) | Activin receptor type IIB, ACTR-IIB |
4 | W, X, e, f, k... | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 24 | Chemie (NAG) | |||
5 | X, e, k, F, K... | SODIUM ION | non-polymer | 23.0 | 6 | Chemie (NA) |
Sequence modifications
C, D, I, J, O, P, U, V, c, d, i, j: 22 - 118 (UniProt: P37023)
E, F, K, L, Q, R, W, X, e, f, k, l: 1 - 116 (UniProt: Q13705)
PDB | External Database | Details |
---|---|---|
Gly 20 | - | expression tag |
Ala 21 | - | expression tag |
Ser 119 | - | expression tag |
Gly 120 | - | expression tag |
Asp 121 | - | expression tag |
Asp 122 | - | expression tag |
Asp 123 | - | expression tag |
Asp 124 | - | expression tag |
Lys 125 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
Ala 0 | - | expression tag |
Gly 117 | - | expression tag |
Asp 118 | - | expression tag |
Asp 119 | - | expression tag |
Asp 120 | - | expression tag |
Asp 121 | - | expression tag |
Lys 122 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 36 |
Total formula weight | 453769.3 | |
Non-Polymers* | Number of molecules | 30 |
Total formula weight | 5446.9 | |
All* | Total formula weight | 459216.2 |