4ELM

Crystal structure of the mouse CD1d-lysosulfatide-Hy19.3 TCR complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, C)	Antigen-presenting glycoprotein CD1d1	polymer	285	32632.7	2	UniProt (P11609) Pfam (PF16497) Pfam (PF07654)	Mus musculus (mouse)
2	C, D (B, D)	Beta-2 microglobulin	polymer	99	11660.4	2	UniProt (Q91XJ8) Pfam (PF07654) UniProt (by SIFTS) (P01887)	Mus musculus (mouse)	Uncharacterized protein
3	E, G (E, G)	Hy19.3 TCR alpha chain (mouse variable domain, human constant domain)	polymer	208	23209.5	2		Mus musculus (mouse)
4	F, H (F, H)	Hy19.3 TCR beta chain (mouse variable domain, human constant domain)	polymer	244	27993.6	2		Mus musculus (mouse)
5	I (I)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
6	J (J)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		732.7	1	In PDB GlyTouCan (G32152BH)
7	K, L, O, P (A, C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
8	M, Q (A, C)	(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl 3-O-sulfo-beta-D-galactopyranoside	non-polymer		541.7	2	Chemie (SGF)
9	N, R (A, C)	PALMITIC ACID	non-polymer		256.4	2	Chemie (PLM)

Sequence modifications

A, C: 1 - 279 (UniProt: P11609)

PDB	External Database	Details
His 201	Asp 219	SEE REMARK 999
His 280	-	expression tag
His 281	-	expression tag
His 282	-	expression tag
His 283	-	expression tag
His 284	-	expression tag
His 285	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	190992.3
Branched	Number of molecules	2
	Total formula weight	1157.1
Non-Polymers*	Number of molecules	8
	Total formula weight	2481.1
All*	Total formula weight	194630.5

*Water molecules are not included.