4EBD
Conformationally Restrained North-methanocarba-2'-deoxyadenosine Corrects the Error-Prone Nature of Human DNA Polymerase Iota
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase iota | polymer | 420 | 47027.3 | 1 | UniProt (Q9UNA4) Pfam (PF00817) Pfam (PF21999) Pfam (PF11799) | Homo sapiens (human) | Eta2, RAD30 homolog B |
| 2 | B (P) | 5'-D(P*AP*GP*GP*AP*CP*CP*(DOC))-3' | polymer | 7 | 2091.4 | 1 | |||
| 3 | C (T) | 5'-D(P*CP*TP*GP*GP*GP*TP*CP*CP*T)-3' | polymer | 9 | 2722.8 | 1 | |||
| 4 | D (A) | South-methanocarba-2'-deoxyadenosine triphosphate | non-polymer | 501.2 | 1 | Chemie (0OJ) | |||
| 5 | E, F, G (A) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 6 | H, I (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | J, K, L (A, P, T) | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 51841.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 805.6 | |
| All* | Total formula weight | 52647.2 |
