4E7R

Thrombin in complex with 3-amidinophenylalanine inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	L, M	Thrombin light chain	polymer	36	4096.5	2	UniProt (P00734) Pfam (PF09396) In PDB	Homo sapiens (human)
2	H, G	Thrombin heavy chain	polymer	259	29780.2	2	UniProt (P00734) Pfam (PF00089) In PDB	Homo sapiens (human)
3	I, J	Hirudin variant-2	polymer	11	1491.5	2	UniProt (P09945) In PDB	Hirudo medicinalis
4	H, G	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
5	H, G	3-[(2S)-3-[4-(2-aminoethyl)piperidin-1-yl]-2-{[(2',4'-dichlorobiphenyl-3-yl)sulfonyl]amino}-3-oxopropyl]benzenecarboximidamide	non-polymer		602.6	2	Chemie (0NW)
6	H, G	SODIUM ION	non-polymer		23.0	4	Chemie (NA)
7	H, G	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
8	H, G	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
9		water	water		18.0	265	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	70736.6
Non-Polymers*	Number of molecules	13
	Total formula weight	2205.8
All*	Total formula weight	72942.3

*Water molecules are not included.