4E7R

Thrombin in complex with 3-amidinophenylalanine inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
G	0004252	molecular_function	serine-type endopeptidase activity
G	0005509	molecular_function	calcium ion binding
G	0006508	biological_process	proteolysis
G	0007596	biological_process	blood coagulation
H	0004252	molecular_function	serine-type endopeptidase activity
H	0005509	molecular_function	calcium ion binding
H	0006508	biological_process	proteolysis
H	0007596	biological_process	blood coagulation
L	0004252	molecular_function	serine-type endopeptidase activity
L	0005576	cellular_component	extracellular region
L	0006508	biological_process	proteolysis
L	0007596	biological_process	blood coagulation
M	0004252	molecular_function	serine-type endopeptidase activity
M	0005576	cellular_component	extracellular region
M	0006508	biological_process	proteolysis
M	0007596	biological_process	blood coagulation

Functional Information from PROSITE/UniProt

site_id	PS00134
Number of Residues	6
Details	TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC

Chain	Residue	Details
H	LEU53-CYS58

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site_id	PS00135
Number of Residues	12
Details	TRYPSIN_SER Serine proteases, trypsin family, serine active site. DAceGDSGGPFV

Chain	Residue	Details
H	ASP189-VAL200

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: Sulfotyrosine => ECO:0000269|PubMed:3513162

Chain	Residue	Details
I	TYS563
J	TYS1563
H	SER195
G	HIS1057
G	ASP1102
G	SER1195

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site_id	SWS_FT_FI2
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19139490, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19838169, ECO:0000269|PubMed:873923

Chain	Residue	Details
H	ASN60
G	ASN1060

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