4E7I
PFV intasome freeze-trapped prior to 3'-processing, Mn-bound form (UI-Mn)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Pro-Pol polyprotein | polymer | 395 | 44456.7 | 2 | UniProt (P14350) Pfam (PF17921) Pfam (PF00665) Pfam (PF18103) | Human spumaretrovirus (SFVcpz(hu)) | Pr125Pol, Protease/Reverse transcriptase/ribonuclease H, p87Pro-RT-RNaseH, Protease/Reverse transcriptase, p65Pro-RT, Ribonuclease H, RNase H, Integrase, IN, p42In |
| 2 | C (C) | DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3') | polymer | 19 | 5834.8 | 1 | synthetic DNA | ||
| 3 | D (D) | DNA (5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*AP*AP*T)-3') | polymer | 19 | 5812.8 | 1 | synthetic DNA | ||
| 4 | E (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | F, G, Q (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 3 | Chemie (MN) | |||
| 6 | H, I, N, R (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 7 | J, K, L, M, O... (A, B, C, D) | GLYCEROL | non-polymer | 92.1 | 9 | Chemie (GOL) | |||
| 8 | P (A) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 9 | S (B) | HEXANE-1,6-DIOL | non-polymer | 118.2 | 1 | Chemie (HEZ) | |||
| 10 | AA, X, Y, Z (D, A, B, C) | water | water | 18.0 | 267 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 392 (UniProt: P14350)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ser 217 | Gly 968 | variant |
| Gly 218 | Ser 969 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 100561.0 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 1756.7 | |
| All* | Total formula weight | 102317.7 |
