4E7I
PFV intasome freeze-trapped prior to 3'-processing, Mn-bound form (UI-Mn)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Pro-Pol polyprotein | polymer | 395 | 44456.7 | 2 | UniProt (P14350) Pfam (PF17921) Pfam (PF00665) Pfam (PF18103) In PDB | Human spumaretrovirus (SFVcpz(hu)) | Pr125Pol, Protease/Reverse transcriptase/ribonuclease H, p87Pro-RT-RNaseH, Protease/Reverse transcriptase, p65Pro-RT, Ribonuclease H, RNase H, Integrase, IN, p42In |
2 | C | DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3') | polymer | 19 | 5834.8 | 1 | synthetic DNA | ||
3 | D | DNA (5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*AP*AP*T)-3') | polymer | 19 | 5812.8 | 1 | synthetic DNA | ||
4 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
5 | A, B | MANGANESE (II) ION | non-polymer | 54.9 | 3 | Chemie (MN) | |||
6 | A, B | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
7 | A, B, C, D | GLYCEROL | non-polymer | 92.1 | 9 | Chemie (GOL) | |||
8 | A | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
9 | B | HEXANE-1,6-DIOL | non-polymer | 118.2 | 1 | Chemie (HEZ) | |||
10 | water | water | 18.0 | 267 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 392 (UniProt: P14350)
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Pro -1 | - | expression tag |
Gly 0 | - | expression tag |
Ser 217 | Gly 968 | variant |
Gly 218 | Ser 969 | variant |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 100561.0 | |
Non-Polymers* | Number of molecules | 19 |
Total formula weight | 1756.7 | |
All* | Total formula weight | 102317.7 |