4E3X

Crystal Structure of Mus musculus 1-pyrroline-5-carboxylate dehydrogenase cryoprotected in proline

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial	polymer	563	61954.2	2	UniProt (Q8CHT0) Pfam (PF00171) In PDB	Mus musculus (mouse)	P5C dehydrogenase, Aldehyde dehydrogenase family 4 member A1
2	A, B	PROLINE	non-polymer		115.1	7	Chemie (PRO)
3	A	3,6,9,12,15,18-HEXAOXAICOSANE	non-polymer		294.4	1	Chemie (16P)
4	A	TRIETHYLENE GLYCOL	non-polymer		150.2	1	Chemie (PGE)
5		water	water		18.0	882	Chemie (HOH)

Sequence modifications

A, B: 22 - 563 (UniProt: Q8CHT0)

PDB	External Database	Details
Met 1	-	expression tag
Gly 2	-	expression tag
Ser 3	-	expression tag
Ser 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
Ser 11	-	expression tag
Ser 12	-	expression tag
Gly 13	-	expression tag
Leu 14	-	expression tag
Val 15	-	expression tag
Pro 16	-	expression tag
Arg 17	-	expression tag
Gly 18	-	expression tag
Ser 19	-	expression tag
His 20	-	expression tag
Met 21	-	expression tag
Ala 33	Thr 32	conflict
Thr 61	Met 60	conflict
Lys 468	Gln 467	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	123908.4
Non-Polymers*	Number of molecules	9
	Total formula weight	1250.5
All*	Total formula weight	125158.9

*Water molecules are not included.