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4E18

Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Vinculinpolymer26329379.91UniProt (P12003)
Pfam (PF01044)
Gallus gallus (chicken)
2B
(B)
Catenin alpha-1polymer596431.21UniProt (P26231)Mus musculus (mouse)Alpha E-catenin, 102 kDa cadherin-associated protein, CAP102
3C, D
(A, B)
waterwater18.074Chemie (HOH)
Sequence modifications
A: 1 - 259 (UniProt: P12003)
PDBExternal DatabaseDetails
Gly -3-expression tag
Gly -2-expression tag
Ile -1-expression tag
Gln 0-expression tag
B: 302 - 356 (UniProt: P26231)
PDBExternal DatabaseDetails
Gly -3-expression tag
Gly -2-expression tag
Ile -1-expression tag
Gln 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight35811.1
All*Total formula weight35811.1
*Water molecules are not included.

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PDB entries from 2025-07-16

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