4E0S
Crystal Structure of C5b-6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Complement C5 | polymer | 1676 | 188526.1 | 1 | UniProt (P01031) Pfam (PF17790) Pfam (PF07677) Pfam (PF01759) Pfam (PF01835) Pfam (PF17791) Pfam (PF17789) Pfam (PF07703) Pfam (PF01821) Pfam (PF00207) Pfam (PF07678) Pfam (PF21309) In PDB | Homo sapiens (human) | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, Complement C5 beta chain, Complement C5 alpha chain, C5a anaphylatoxin, Complement C5 alpha' chain |
| 2 | B | Complement component C6 | polymer | 913 | 102541.3 | 1 | UniProt (P13671) Pfam (PF00090) Pfam (PF00057) Pfam (PF01823) Pfam (PF21195) Pfam (PF00084) Pfam (PF07648) In PDB | Homo sapiens (human) | |
| 3 | C, D | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 4 | E | beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose | branched | 326.3 | 1 | In PDB GlyTouCan (G36855WW) | |||
| 5 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | B | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 7 | B | alpha-D-mannopyranose | non-polymer | 180.2 | 4 | Chemie (MAN) |
Sequence modifications
A: 1 - 1676 (UniProt: P01031)
| PDB | External Database | Details |
|---|---|---|
| Ile 802 | Val 802 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 291067.4 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1175.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 783.7 | |
| All* | Total formula weight | 293026.2 |
