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4DPD

WILD TYPE PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (PfDHFR-TS), DHF COMPLEX, NADP+, dUMP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Bifunctional dihydrofolate reductase-thymidylate synthasepolymer60871828.02UniProt (A7UD81)
Pfam (PF00186)
Pfam (PF00303)
Plasmodium falciparum
2C
(A)
DIHYDROFOLIC ACIDnon-polymer443.41Chemie (DHF)
3D
(A)
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.41Chemie (NAP)
4E, F
(A, B)
2'-DEOXYURIDINE 5'-MONOPHOSPHATEnon-polymer308.22Chemie (UMP)
5G, H
(A, B)
waterwater18.0407Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight143656.0
Non-Polymers*Number of molecules4
Total formula weight1803.2
All*Total formula weight145459.2
*Water molecules are not included.

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PDB entries from 2025-07-30

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