4DM6
Crystal structure of RARb LBD homodimer in complex with TTNPB
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Retinoic acid receptor beta | polymer | 267 | 30179.0 | 2 | UniProt (P10826) Pfam (PF00104) In PDB | Homo sapiens (human) | RAR-beta, HBV-activated protein, Nuclear receptor subfamily 1 group B member 2, RAR-epsilon |
2 | E, F | Nuclear receptor coactivator 1 | polymer | 25 | 2806.2 | 2 | UniProt (Q15788) Pfam (PF08832) In PDB | Homo sapiens | NCoA-1, Class E basic helix-loop-helix protein 74, bHLHe74, Protein Hin-2, RIP160, Renal carcinoma antigen NY-REN-52, Steroid receptor coactivator 1, SRC-1 |
3 | A, B | 4-[(1E)-2-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)PROP-1-ENYL]BENZOIC ACID | non-polymer | 348.5 | 2 | Chemie (TTB) | |||
4 | water | water | 18.0 | 178 | Chemie (HOH) |
Sequence modifications
A, B: 178 - 423 (UniProt: P10826)
PDB | External Database | Details |
---|---|---|
Met 157 | - | initiating methionine |
Gly 158 | - | expression tag |
Ser 159 | - | expression tag |
Ser 160 | - | expression tag |
His 161 | - | expression tag |
His 162 | - | expression tag |
His 163 | - | expression tag |
His 164 | - | expression tag |
His 165 | - | expression tag |
His 166 | - | expression tag |
Ser 167 | - | expression tag |
Ser 168 | - | expression tag |
Gly 169 | - | expression tag |
Leu 170 | - | expression tag |
Val 171 | - | expression tag |
Pro 172 | - | expression tag |
Arg 173 | - | expression tag |
Gly 174 | - | expression tag |
Ser 175 | - | expression tag |
His 176 | - | expression tag |
Met 177 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 65970.2 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 697.0 | |
All* | Total formula weight | 66667.2 |