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4DJE

Crystal structure of folate-bound corrinoid iron-sulfur protein (CFeSP) in complex with its methyltransferase (MeTr), co-crystallized with folate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferasepolymer26228638.12UniProt (Q46389)
Pfam (PF00809)
Moorella thermoacetica
2C, E
(C, E)
Corrinoid/iron-sulfur protein large subunitpolymer44648207.02UniProt (Q07340)
Pfam (PF04060)
Pfam (PF03599)
Moorella thermoaceticaC/Fe-SP
3D, F
(D, F)
Corrinoid/iron-sulfur protein small subunitpolymer32335107.22UniProt (Q07341)
Pfam (PF03599)
Moorella thermoaceticaC/Fe-SP
4G, J
(A, B)
5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACIDnon-polymer459.52Chemie (C2F)
5H, I
(A, B)
CALCIUM IONnon-polymer40.12Chemie (CA)
6K, M
(C, E)
IRON/SULFUR CLUSTERnon-polymer351.62Chemie (SF4)
7L, N
(C, E)
COBALAMINnon-polymer1330.42Chemie (B12)
8O, P, Q, R, S
(A, B, D, E, F)
waterwater18.012Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight223904.6
Non-Polymers*Number of molecules8
Total formula weight4363.1
All*Total formula weight228267.6
*Water molecules are not included.

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PDB entries from 2025-12-24

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