4DGL
Crystal Structure of the CK2 Tetrameric Holoenzyme
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Casein kinase II subunit beta | polymer | 215 | 24969.4 | 2 | UniProt (P67870) Pfam (PF01214) | Homo sapiens (human) | CK II beta, Phosvitin, Protein G5a |
| 2 | C, D (C, D) | Casein kinase II subunit alpha | polymer | 335 | 40060.8 | 2 | UniProt (P68400) Pfam (PF00069) | Homo sapiens (human) | CK II alpha |
| 3 | E, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence modifications
C, D: 1 - 335 (UniProt: P68400)
| PDB | External Database | Details |
|---|---|---|
| Arg 125 | Tyr 125 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 130060.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 130191.2 |
