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4DFK

large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with 5-(N-(10-hydroxydecanoyl)-aminopentinyl)-2-dUTP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase I, thermostablepolymer54060937.01UniProt (P19821)
Pfam (PF09281)
Pfam (PF00476)
Thermus aquaticusTaq polymerase 1
2B
(B)
5'-d(GACCACGGCGC DOC)-3'polymer123617.41
3C
(C)
5'-d(AAAAGGCGCCGTGGTC)-3'polymer164948.21
4D
(A)
2'-deoxy-5-{5-[(10-hydroxydecanoyl)amino]pent-1-yn-1-yl}uridine 5'-(tetrahydrogen triphosphate)non-polymer719.51Chemie (0L5)
5E, F, H, L, P...
(A, B, C)
MAGNESIUM IONnon-polymer24.36Chemie (MG)
6G, I, N
(A)
1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
7J, K, M, O, R
(A, C)
FORMIC ACIDnon-polymer46.05Chemie (FMT)
8S, T, U
(A, B, C)
waterwater18.0367Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight69502.6
Non-Polymers*Number of molecules15
Total formula weight1281.7
All*Total formula weight70784.2
*Water molecules are not included.

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PDB entries from 2025-12-17

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