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4CMQ

Crystal structure of Mn-bound S.pyogenes Cas9

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1polymer1372158986.12UniProt (Q99ZW2)
Pfam (PF16593)
Pfam (PF16592)
Pfam (PF13395)
Pfam (PF22702)
Pfam (PF16595)
STREPTOCOCCUS PYOGENESCAS9
2C, D, E, F, G...
(A, B)
MANGANESE (II) IONnon-polymer54.913Chemie (MN)
3J, K, L, S, T...
(A, B)
SULFATE IONnon-polymer96.16Chemie (SO4)
Sequence modifications
A, B: 1 - 1368 (UniProt: Q99ZW2)
PDBExternal DatabaseDetails
Gly -3-expression tag
Ala -2-expression tag
Ala -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight317972.2
Non-Polymers*Number of molecules19
Total formula weight1290.6
All*Total formula weight319262.8
*Water molecules are not included.

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