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4CFL

N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH LY303511

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
BRD4 PROTEINpolymer12715099.41UniProt (Q6NXE4)
Pfam (PF00439)
UniProt (by SIFTS) (O60885)
HOMO SAPIENS (HUMAN)BROMODOMAIN CONTAINING PROTEIN 4
2B
(A)
8-phenyl-2-piperazin-1-yl-chromen-4-onenon-polymer306.41Chemie (8DQ)
3C
(A)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
4D
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
5E
(A)
waterwater18.0289Chemie (HOH)
Sequence modifications
A: 42 - 168 (UniProt: Q6NXE4)
PDBExternal DatabaseDetails
Met 43Thr 43conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight15099.4
Non-Polymers*Number of molecules3
Total formula weight460.5
All*Total formula weight15559.9
*Water molecules are not included.

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PDB entries from 2025-06-18

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