4CDG
Crystal structure of the Bloom's syndrome helicase BLM in complex with Nanobody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | BLOOM SYNDROME PROTEIN | polymer | 673 | 76705.2 | 2 | UniProt (P54132) Pfam (PF00270) Pfam (PF00271) Pfam (PF16124) Pfam (PF09382) Pfam (PF00570) In PDB | HOMO SAPIENS (HUMAN) | BLOOM SYNDROME HELICASE, DNA HELICASE, RECQ-LIKE TYPE 2, RECQ2, RECQ PROTEIN-LIKE 3 |
| 2 | C, D | NANOBODY | polymer | 147 | 16170.3 | 2 | LAMA GLAMA (LLAMA) | ||
| 3 | A, B | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 4 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
A, B: 636 - 1298 (UniProt: P54132)
| PDB | External Database | Details |
|---|---|---|
| Ser 634 | - | expression tag |
| Met 635 | - | expression tag |
| Met 1299 | - | expression tag |
| Ser 1300 | - | expression tag |
| Glu 1301 | - | expression tag |
| Asn 1302 | - | expression tag |
| Leu 1303 | - | expression tag |
| Tyr 1304 | - | expression tag |
| Phe 1305 | - | expression tag |
| Gln 1306 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 185751.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 985.2 | |
| All* | Total formula weight | 186736.3 |
