4C9Z
Crystal structure of Siah1 at 1.95 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | E3 UBIQUITIN-PROTEIN LIGASE SIAH1 | polymer | 195 | 21921.1 | 2 | UniProt (Q8IUQ4) Pfam (PF21361) Pfam (PF03145) | HOMO SAPIENS (HUMAN) | SEVEN IN ABSENTIA HOMOLOG 1, SIAH-1, SIAH-1A |
| 2 | C, D, M, N (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | E, F, G, R (A, B) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 4 | H, I, J (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | K, P, Q (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | L, O (A, B) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 2 | Chemie (TRS) | |||
| 7 | S, T (A, B) | water | water | 18.0 | 217 | Chemie (HOH) |
Sequence modifications
A, B: 91 - 282 (UniProt: Q8IUQ4)
| PDB | External Database | Details |
|---|---|---|
| Gly 88 | - | expression tag |
| His 89 | - | expression tag |
| Met 90 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43842.2 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1212.2 | |
| All* | Total formula weight | 45054.4 |
