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4BW5

Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
POTASSIUM CHANNEL SUBFAMILY K MEMBER 10polymer28231060.14UniProt (P57789)
Pfam (PF00520)
Pfam (PF07885)
HOMO SAPIENS (HUMAN)OUTWARD RECTIFYING POTASSIUM CHANNEL PROTEIN TREK-2, TREK-2 K(+) CHANNEL SUBUNIT
2E, F, G, H, M...
(A, C)
POTASSIUM IONnon-polymer39.18Chemie (K)
3I, J
(A)
CADMIUM IONnon-polymer112.42Chemie (CD)
4K, L
(A, B)
1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINEnon-polymer790.12Chemie (PC1)
Sequence modifications
A, B, C, D: 67 - 340 (UniProt: P57789)
PDBExternal DatabaseDetails
Met 66-expression tag
Ala 341-expression tag
Glu 342-expression tag
Asn 343-expression tag
Leu 344-expression tag
Tyr 345-expression tag
Phe 346-expression tag
Gln 347-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight124240.4
Non-Polymers*Number of molecules12
Total formula weight2117.9
All*Total formula weight126358.3
*Water molecules are not included.

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PDB entries from 2025-07-23

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