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4BVV

Identification of small molecule inhibitors selective for apo(a) kringles KIV-7, KIV-10 and KV.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
APOLIPOPROTEIN(A)polymer819186.41UniProt (P08519)
Pfam (PF00051)
HOMO SAPIENS (HUMAN)APO(A), LP(A)
2B
(A)
1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACIDnon-polymer331.31Chemie (CPF)
3C
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
4D
(A)
waterwater18.088Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight9186.4
Non-Polymers*Number of molecules2
Total formula weight427.4
All*Total formula weight9613.8
*Water molecules are not included.

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PDB entries from 2024-10-30

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