4BVV
Identification of small molecule inhibitors selective for apo(a) kringles KIV-7, KIV-10 and KV.
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE CPF A 1081 |
Chain | Residue |
A | PHE3 |
A | LEU71 |
A | PHE72 |
A | SER34 |
A | THR35 |
A | ASP55 |
A | ASP57 |
A | ILE58 |
A | ASN59 |
A | TRP62 |
A | TYR64 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 A 1082 |
Chain | Residue |
A | ASP0 |
A | TYR9 |
A | LYS12 |
A | LYS13 |
Functional Information from PROSITE/UniProt
site_id | PS00021 |
Number of Residues | 14 |
Details | KRINGLE_1 Kringle domain signature. YCRNpdgdingpWC |
Chain | Residue | Details |
A | TYR50-CYS63 |