4BQH
Crystal structure of the uridine diphosphate N-acetylglucosamine pyrophosphorylase from Trypanosoma brucei in complex with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE | polymer | 549 | 60598.8 | 1 | UniProt (Q386Q8) Pfam (PF01704) | TRYPANOSOMA BRUCEI | |
| 2 | B, D (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | C (A) | (3S)-3-[2-(1,3-benzodioxol-5-yl)-2-oxidanylidene-ethyl]-4-bromanyl-5-methyl-3-oxidanyl-1H-indol-2-one | non-polymer | 404.2 | 1 | Chemie (9VU) | |||
| 4 | E (A) | water | water | 18.0 | 409 | Chemie (HOH) |
Sequence modifications
A: 1 - 545 (UniProt: Q386Q8)
| PDB | External Database | Details |
|---|---|---|
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 60598.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 596.3 | |
| All* | Total formula weight | 61195.1 |
