4BQH
Crystal structure of the uridine diphosphate N-acetylglucosamine pyrophosphorylase from Trypanosoma brucei in complex with inhibitor
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003977 | molecular_function | UDP-N-acetylglucosamine diphosphorylase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0006011 | biological_process | UDP-glucose metabolic process |
A | 0006048 | biological_process | UDP-N-acetylglucosamine biosynthetic process |
A | 0016740 | molecular_function | transferase activity |
A | 0016779 | molecular_function | nucleotidyltransferase activity |
A | 0020015 | cellular_component | glycosome |
A | 0070569 | molecular_function | uridylyltransferase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 A 1538 |
Chain | Residue |
A | GLY510 |
A | LEU511 |
A | ARG512 |
A | HOH2388 |
A | HOH2389 |
A | HOH2391 |
site_id | AC2 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE 9VU A 1539 |
Chain | Residue |
A | HIS49 |
A | PHE50 |
A | SER207 |
A | VAL209 |
A | GLY232 |
A | ALA236 |
A | ALA239 |
A | ALA367 |
A | MET370 |
A | LYS371 |
A | TYR376 |
A | HOH2056 |
A | HOH2065 |
A | HOH2315 |
A | GLY44 |
A | VAL45 |
A | ASP46 |
site_id | AC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 A 1540 |
Chain | Residue |
A | HIS202 |
A | ARG245 |
A | HIS263 |
A | HOH2238 |
A | HOH2239 |
A | HOH2409 |