4BKU

Enoyl-ACP reductase FabI from Burkholderia pseudomallei with cofactor NADH and inhibitor PT155

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH]	polymer	276	29325.4	1	UniProt (I1WHT9) UniProt (by SIFTS) (A0A0H3HP34)	BURKHOLDERIA PSEUDOMALLEI	ENOYL-ACP REDUCTASE FABI
2	B (A)	1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE	non-polymer		665.4	1	Chemie (NAI) PubChem (928) PubChem (11250888) PubChem (12309341) PubChem (16219774) PubChem (44119956) PubChem (44415182) PubChem (439153) PubChem (124934832) PubChem (126455899) PubChem (134693949) PubChem (12309339) PubChem (12309347) PubChem (140875346) PubChem (162951601) PubChem (162951600) PubChem (164575491) PubChem (169545638) PubChem (170905224) PubChem (174316169) PubChem (94865921) PubChem (94865923) PubChem (124432988) PubChem (124934831) PubChem (124934833) PubChem (129607000) PubChem (129628338) PubChem (146167236) PubChem (162951602) PubChem (174084875)
3	C (A)	5-(4-amino-2-methylphenoxy)-2-hexyl-4-hydroxy-1-methylpyridinium	non-polymer		314.4	1	Chemie (1S5) PubChem (73437603)
4	D (A)	water	water		18.0	343	Chemie (HOH)

Sequence modifications

A: 1 - 263 (UniProt: I1WHT9)

PDB	External Database	Details
Lys 264	-	expression tag
Leu 265	-	expression tag
Ala 266	-	expression tag
Ala 267	-	expression tag
Ala 268	-	expression tag
Leu 269	-	expression tag
Glu 270	-	expression tag
His 271	-	expression tag
His 272	-	expression tag
His 273	-	expression tag
His 274	-	expression tag
His 275	-	expression tag
His 276	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	29325.4
Non-Polymers*	Number of molecules	2
	Total formula weight	979.9
All*	Total formula weight	30305.3

*Water molecules are not included.