4BKU

Enoyl-ACP reductase FabI from Burkholderia pseudomallei with cofactor NADH and inhibitor PT155

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004318	molecular_function	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A	0006633	biological_process	fatty acid biosynthetic process
A	0016491	molecular_function	oxidoreductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	30
Details	BINDING SITE FOR RESIDUE NAI A 1259

Chain	Residue
A	GLY13
A	ILE92
A	GLY93
A	LEU144
A	SER145
A	LYS163
A	ALA189
A	GLY190
A	PRO191
A	ILE192
A	1S51260
A	LEU15
A	HOH2038
A	HOH2039
A	HOH2044
A	HOH2053
A	HOH2101
A	HOH2198
A	HOH2338
A	HOH2339
A	HOH2340
A	HOH2341
A	SER19
A	HOH2342
A	ILE20
A	VAL40
A	CYS63
A	ASP64
A	VAL65
A	SER91

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site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE 1S5 A 1260

Chain	Residue
A	GLY93
A	ALA95
A	ILE100
A	PRO154
A	ASN155
A	TYR156
A	PHE203
A	ILE206
A	NAI1259

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