4BKU
Enoyl-ACP reductase FabI from Burkholderia pseudomallei with cofactor NADH and inhibitor PT155
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE NAI A 1259 |
| Chain | Residue |
| A | GLY13 |
| A | ILE92 |
| A | GLY93 |
| A | LEU144 |
| A | SER145 |
| A | LYS163 |
| A | ALA189 |
| A | GLY190 |
| A | PRO191 |
| A | ILE192 |
| A | 1S51260 |
| A | LEU15 |
| A | HOH2038 |
| A | HOH2039 |
| A | HOH2044 |
| A | HOH2053 |
| A | HOH2101 |
| A | HOH2198 |
| A | HOH2338 |
| A | HOH2339 |
| A | HOH2340 |
| A | HOH2341 |
| A | SER19 |
| A | HOH2342 |
| A | ILE20 |
| A | VAL40 |
| A | CYS63 |
| A | ASP64 |
| A | VAL65 |
| A | SER91 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 1S5 A 1260 |
| Chain | Residue |
| A | GLY93 |
| A | ALA95 |
| A | ILE100 |
| A | PRO154 |
| A | ASN155 |
| A | TYR156 |
| A | PHE203 |
| A | ILE206 |
| A | NAI1259 |
