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4BDV

CRYSTAL STRUCTURE OF A TRUNCATED B-DOMAIN HUMAN FACTOR VIII

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
FACTOR VIIIA HEAVY CHAIN, 92 KDA ISOFORM, B DOMAINpolymer76087107.41UniProt (P00451)
Pfam (PF07732)
HOMO SAPIENS (HUMAN)COAGULATION FACTOR VIII, ANTIHEMOPHILIC FACTOR, AHF, PROCOAGULANT COMPONENT
2B
(B)
FACTOR VIIIA LIGHT CHAINpolymer68579241.81UniProt (P00451)
Pfam (PF07731)
Pfam (PF00754)
HOMO SAPIENS (HUMAN)COAGULATION FACTOR VIII, ANTIHEMOPHILIC FACTOR, AHF, PROCOAGULANT COMPONENT
3C
(C)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.41In PDB
GlyTouCan (G42666HT)
4D
(D)
beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched910.81In PDB
GlyTouCan (G89225LT)
5E
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
6F
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
7G, I
(A, B)
1,2-ETHANEDIOLnon-polymer62.12Chemie (EDO)
8H
(B)
COPPER (I) IONnon-polymer63.51Chemie (CU1)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight166349.2
BranchedNumber of molecules2
Total formula weight1335.2
Non-Polymers*Number of molecules5
Total formula weight293.2
All*Total formula weight167977.6
*Water molecules are not included.

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PDB entries from 2024-11-13

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