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4B4O

Crystal Structure of human epimerase family protein SDR39U1 (isoform2) with NADPH

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...EPIMERASE FAMILY PROTEIN SDR39U1polymer29832055.08UniProt (Q9NRG7)
Pfam (PF01370)
Pfam (PF08338)
In PDB
HOMO SAPIENS (HUMAN)SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 39U MEMBER 1
2A, B, C, D, E...NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer745.48Chemie (NDP)
3A, B, C, D, E...2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOLnon-polymer354.48Chemie (PE4)
4waterwater18.0520Chemie (HOH)
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 291 (UniProt: Q9NRG7)
PDBExternal DatabaseDetails
Ala 292-expression tag
Glu 293-expression tag
Asn 294-expression tag
Leu 295-expression tag
Tyr 296-expression tag
Phe 297-expression tag
Gln 298-expression tag
Leu 79Ile 79engineered mutation
Phe 232Leu 232engineered mutation
Arg 270Gln 270engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight256439.7
Non-Polymers*Number of molecules16
Total formula weight8798.9
All*Total formula weight265238.6
*Water molecules are not included.

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PDB entries from 2024-07-31

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