4B4O
Crystal Structure of human epimerase family protein SDR39U1 (isoform2) with NADPH
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | EPIMERASE FAMILY PROTEIN SDR39U1 | polymer | 298 | 32055.0 | 8 | UniProt (Q9NRG7) Pfam (PF01370) Pfam (PF08338) In PDB | HOMO SAPIENS (HUMAN) | SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 39U MEMBER 1 |
2 | A, B, C, D, E... | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 8 | Chemie (NDP) | |||
3 | A, B, C, D, E... | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL | non-polymer | 354.4 | 8 | Chemie (PE4) | |||
4 | water | water | 18.0 | 520 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 291 (UniProt: Q9NRG7)
PDB | External Database | Details |
---|---|---|
Ala 292 | - | expression tag |
Glu 293 | - | expression tag |
Asn 294 | - | expression tag |
Leu 295 | - | expression tag |
Tyr 296 | - | expression tag |
Phe 297 | - | expression tag |
Gln 298 | - | expression tag |
Leu 79 | Ile 79 | engineered mutation |
Phe 232 | Leu 232 | engineered mutation |
Arg 270 | Gln 270 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 256439.7 | |
Non-Polymers* | Number of molecules | 16 |
Total formula weight | 8798.9 | |
All* | Total formula weight | 265238.6 |