4B21

Unprecedented sculpting of DNA at abasic sites by DNA glycosylase homolog Mag2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	PROBABLE DNA-3-METHYLADENINE GLYCOSYLASE 2	polymer	232	26362.1	1	UniProt (O94468) Pfam (PF00730) In PDB	SCHIZOSACCHAROMYCES POMBE	MAG2,3-METHYLADENINE DNA GLYCOSIDASE 2,3MEA DNA GLYCOSYLASE 2
2	X	5'-D(*GP*CP*TP*AP*CP*3DRP*GP*AP*TP*CP*GP)-3'	polymer	11	3225.1	1		SYNTHETIC CONSTRUCT
3	Y	5'-D(*CP*GP*AP*TP*CP*GP*GP*TP*AP*GP)-3'	polymer	10	3085.0	1		SYNTHETIC CONSTRUCT
4	A	beta-D-glucopyranose	non-polymer		180.2	1	Chemie (BGC)
5	A, Y	PHOSPHATE ION	non-polymer		95.0	3	Chemie (PO4)
6		water	water		18.0	255	Chemie (HOH)

Sequence modifications

A: 1 - 213 (UniProt: O94468)

PDB	External Database	Details
Met -18	-	expression tag
Gly -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	32672.2
Non-Polymers*	Number of molecules	4
	Total formula weight	465.1
All*	Total formula weight	33137.3

*Water molecules are not included.