4AZB
Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | BETA-N-ACETYLHEXOSAMINIDASE | polymer | 434 | 47972.5 | 1 | UniProt (P49610) Pfam (PF00728) In PDB | STREPTOCOCCUS PNEUMONIAE | GLYCOSIDE HYDROLASE 20 |
2 | A | O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE | non-polymer | 353.3 | 1 | Chemie (OAN) | |||
3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
4 | A | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
5 | water | water | 18.0 | 298 | Chemie (HOH) |
Sequence modifications
A: 181 - 614 (UniProt: P49610)
PDB | External Database | Details |
---|---|---|
Gly 481 | Trp 449 | engineered mutation |
Gly 482 | Tyr 450 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 47972.5 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 1047.9 | |
All* | Total formula weight | 49020.4 |