4AZB

Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0005975	biological_process	carbohydrate metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE OAN A 1606

Chain	Residue
A	ARG196
A	ASP519
A	EDO1608
A	HOH2038
A	HOH2165
A	HOH2244
A	HOH2274
A	HOH2296
A	HIS297
A	ASP360
A	GLU361
A	TRP439
A	TRP443
A	ASP466
A	TYR469
A	TRP517

---

site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE EDO A 1607

Chain	Residue
A	ASN422

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1608

Chain	Residue
A	TRP443
A	GLU503
A	OAN1606
A	HOH2224

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 1609

Chain	Residue
A	TYR317
A	TYR386
A	HOH2127
A	HOH2297
A	HOH2298

---

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE EDO A 1610

Chain	Residue
A	TYR317

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1611

Chain	Residue
A	LYS452
A	GLU456
A	GLU503
A	HOH2230

---

site_id	AC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 1612

Chain	Residue
A	GLY441
A	PRO500
A	LYS501
A	LYS501
A	THR502
A	HOH2226
A	HOH2228
A	HOH2243

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 1613

Chain	Residue
A	ARG524
A	SER526
A	PRO527
A	SER528

---

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 1614

Chain	Residue
A	LYS532
A	ARG535
A	HIS536

---

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 1615

Chain	Residue
A	HIS213
A	TYR214
A	ARG535

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